MacVector is extremely customizable. If you don’t like the defaults we supply, its very easy to change them. Lets look at restriction enzyme sites. By default we show unique sites in small red letters and sites that cut more than once in small blue letters. But suppose you want something bigger, bolder and, well, more black and white? Here’s how to do it. Hold down the [option] key and choose the Options | Default Symbols menu item. If no sequence windows are open, you don’t even need to hold down the ∫ key. This opens the Default Symbols editor.
In the Results tab, select the Unique Restriction item and change the font e.g. to Helvetica Bold 14.0 pt. Then click on the Restriction item and maybe change that to Helvetica 14.0 pt. I’ve also changed the Symbol pen color to black. Click OK to dismiss the dialog and save the changes, then open up one of your favorite vectors (you do have to re-load sequences for the changes to take effect).