MacVector Pro is now MacVector Pro with Assembler

MacVector Pro now includes Assembler, a powerful sequence assembly plugin that brings sequence assembly directly to your desktop with the same user-friendly interface MacVector users have come to expect. Assembler simplifies the management, assembly, and analysis of all types of sequencing data.

Assembler’s extensive toolkit has always been seamlessly integrated into MacVector, but previously required an additional purchase. In response to the growing availability of sequencing data and to better serve our customers, we have made the decision to include Assembler at no extra cost for all active MacVector users starting in September 2024.

Assembler combines the Assembly Projects manager with a robust sequence assembly toolkit, offering features to handle a wide range of sequencing reads from various platforms. From Sanger reads to PacBio and Nanopore long reads. With six de novo assemblers and two tools for mapping reads to a reference sequence, Assembler provides the necessary tools for efficient and accurate assembly. Users can even perform de novo assembly of genomes up to ~100 Mbp on a standard Mac laptop.

How to upgrade your license to MacVector with Assembler

• Active users: on your next renewal date Assembler will be automatically added. You do not need to do anything (alternatively contact MacVector Support now).
• Inactive users: request an upgrade quote and Assembler will be included at no extra cost.
• New licenses: Assembler will be added to all new licenses.

With MacVector and Assembler you no longer need a powerful Linux server for sequence assembly. Assembler is fully integrated into MacVector and allows you to manage sequencing data with the familiar MacVector style. You can design primers directly on a contig or BLAST that contig to identify it. de novo sequence assembly using Phrap, Velvet and SPAdes with Flye for PacBio and Oxford Nanopore. Reference Sequence Assembly: Map millions of reads against genomes, transcriptomes or other reference sequences using Bowtie2. Compare Genomes: Compare two related annotated genomes to see common or missing genes. Coverage Tab: compare multiple assemblies with expression level comparison. Variant Calling: SNPs and INDELS are visualised on your assembly and supplied in VCF. Bacterial genome tools Tools for finishing bacterial genomes including circularizing genomes. Easy to use interface. Navigating around your assemblies has never been easier. Display an entire contig in the graphical Map and select a read to zoom straight to that region. Click on a base in a contig and see coverage and variants. Heterozygote analysis. Analyse heterozygotes in Sanger trace files or assemblies. Assembly Project manager makes it easy to assemble multiple datasets, reference sequences and assemblies. Work with unaligned reads from an assembly directly in the project. Compare different assemblies. Map multiple datasets against the same reference, or repeat the same assembly with different options. RNA-Seq analysis with read depth visualization and per gene coverage data (RPKM & TPM).

With MacVector/Assembler, there is no need to send your sequencing away or learn complicated software tools. You can analyze your own data with MacVector on your own Mac.