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  • Free teaching licenses!

    It’s that time of year when summer is coming to a close and you need to get ready for teaching again! However, to make you feel a little better, did you know that you can get FREE licenses for teaching purposes? MacVector makes a great teaching tool and we offer free teaching licenses for anyone…

    Read more: Free teaching licenses!
    Aug 21, 2014

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    by

    Chris
    in General, Tips

  • Online updating with Sparkle

    Having to update software is an annoying, but essential, part of modern computing life! All software has bugs that need fixing and good software should add new features as well. We try with MacVector to do both, But that means that from time to time you will need to download and install a new version.…

    Read more: Online updating with Sparkle
    Jul 15, 2014

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    by

    Chris
    in General, Tips

  • Using Applescript to batch convert files.

    Up until MacVector 13 Applescript support was fairly limited. However, with this release we’ve started to expand it. The first enhancement has been to improve the export of files. Now you can export files to any supported format. Over the next few releases this support will be further expanded to include some analysis tools. If…

    Read more: Using Applescript to batch convert files.
    May 23, 2014

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    by

    Chris
    in Tips

  • Accessing BAM files from an Assembly Project file

    All assemblies are stored using the BAM file format. This is a binary file that stores each read and where and which consensus/contig/reference it is mapped against. It is a compressed version of the pure text SAM format. For some post assembly tasks it is necessary to do further processing on the BAM file. To…

    Read more: Accessing BAM files from an Assembly Project file
    Apr 22, 2014

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    by

    Chris
    in Tips

  • de novo assembly with Velvet

    Velvet is a short read aligner that works very well on a wide variety of reads. Velvet excels at de novo assembly of sequencing reads from second and newer generation sequencers. In our latest release, MacVector 13, we’ve added Velvet to Assembler. This joins the existing tools, Phrap for Sanger sequencing reads and Bowtie for…

    Read more: de novo assembly with Velvet
    Apr 7, 2014

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    by

    Chris
    in Releases, Tips

  • Calculating the melting temperature of PCR primers

    Calculating an accurate melting temperature of your oligos, your template and of the predicted product is important to set the cycling parameters of your PCR machine. The Tm calculations in MacVector were updated in MacVector 12.6 to use a more modern algorithm. MacVector has always used thermodynamic “nearest neighbor” calculations, but there were two changes…

    Read more: Calculating the melting temperature of PCR primers
    Apr 7, 2014

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    by

    Chris
    in Releases, Tips

  • Troubleshooting: Resetting MacVector’s preferences

    MacVector generally just works. However, even the most well behaved of applications sometime have problems. If you have restarted the application and restarted your Mac then a good troubleshooting step to perform next is to reset your preferences. For Mountain Lion and earlier deleting the preferences meant opening up Finder, navigating to your ~/Library folder…

    Read more: Troubleshooting: Resetting MacVector’s preferences
    Apr 3, 2014

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    by

    Chris
    in Tips

  • Importing sequences from ENSEMBL

    There’s a few different ways to import annotation from the ENSEMBL database browser, as well as other databases. Using Genbank The easiest way to export from ENSEMBL and keep all annotation is to use the Genbank format. The default format will be FASTA which has no annotation. With Genbank all the annotation is stored in…

    Read more: Importing sequences from ENSEMBL
    Mar 31, 2014

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    by

    Chris
    in Tips, Tutorials

  • Implementing a new activation code for network license users

    When you’ve got a lot of licenses and a lot of computers to manage, a network license is the most effective way of letting your users access their favourite sequence analysis app for the Mac! MacVector network license use the KeyServer network license software from Sassafras. However, in addition to the KeyServer setup MacVector also…

    Read more: Implementing a new activation code for network license users
    Mar 27, 2014

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    by

    Chris
    in Tips

  • Testing primers with MacVector 13

    New to MacVector 13 is the ability to quickly test a pair of primers. Previously to test a pair of primers with the Primer3 tool you needed to modify the expected product and reduce the stringency of all parameters so that your primers would be accepted. Now when you enter a pair of primers into…

    Read more: Testing primers with MacVector 13
    Mar 13, 2014

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    by

    Chris
    in Releases, Tips
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Workflows

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