Migrating your Vector NTI sequence database to MacVector.

ThermoFisher (owners of Invitrogen) have announced that Vector NTI Express is nearing the end of its life and Vector NTI Advanced was terminated quite some time ago. If you are looking for an easy to use sequence analysis application, then look for a reliable and trusted application. MacVector is easy to use, has a comprehensive set of tools and is definitely not going away! MacVector has been the tried and trusted sequence analysis application on the Mac for over 20 years. There are many thousands of happy molecular biologists using MacVector in labs all over the world. Don’t take our word for it, read what our users have to say. What’s more opening Vector NTI files is straightforward.

If you are using Vector NTI Advance 11 or Vector NTI Express

  • Download the Mac or Windows Vector NTI Data Export Tool from ThermoFisher’s website.
  • Run this and migrate your entire sequence database to Genbank format. Note that if you are running macOS Catalina, then Apple’s increased security means you will need to right click, choose Open, then Open again.
  • To open in MacVector simply double click the Genbank file to open it directly within MacVector.
  • When you make changes then save and MacVector will automatically migrate the data into MacVector’s own NUCL format.

  • You can optionally batch process all your files into MacVector format using an Applescript that is supplied within the MacVector application folder.
  • If you are using Vector NTI Advance 10 or earlier

  • Open MacVector
  • Select the Database->Vector NTI Import… menu item
  • Click on the Choose button to locate the Vector NTI database folder on your Mac.
  • MacVector will display a list of all of the sequences available in the database. There is a popup menu to toggle between Nucleic Acid and Protein sequences. The list can be sorted to more easily identify sequence(s) of interest.

  • Select one or more sequences and then click either the To Desktop button to open those sequences in MacVector, or To Disk to save the sequences in MacVector format to a folder on your hard drive.
  • Sequence annotation

    MacVector will read all of the standard features and annotations associated with each sequence. Graphical appearance information is discarded and the highly customizable MacVector graphical features are used instead. If you prefer your sequences to look different then it is easy to curate all graphical features using MacVector’s Auto Annotation tool.

    MacVector ignores any restriction enzyme sites annotated in the database sequence and replaces them with the default dynamic set of sites used by MacVector’s RE Picker. However, all sequence features and related information are preserved. MacVector follows the Genbank format for the features table and is always kept up to date with the latest Genbank release, so where possible MacVector will also migrate any old and deprecated features information contained in the VectorNTI file into the current up to date features nomenclature.

    You will always get a good discount for upgrading to MacVector from Vector NTI.

    Your sequences remain yours

    The MacVector team strongly believe that you should never be locked out of your data. Your data is yours! Even if you have no license of MacVector then you can download MacVector Free and export your data. All versions of MacVector, including MacVector Free, have the tools to migrate sequences in Genbank format.

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