General musings from the MacVector team about sequence analysis, molecular biology, the Mac in general and of course your favorite sequence analysis app for the Mac!

MacVector 12.7 is now out.

We’re pleased to announce that MacVector 12.7 has just been released.

The most exciting new feature is the Cloning Clipboard. We’ve had a lot of user requests over the past few years for help with designing cloning operations and the user feedback we had during the beta testing of MacVector 12.7 makes us think we’ve done it. The Cloning Clipboard makes cloning even complex multi fragment operations easy and quick. You literally drag and drop fragments from the Cloning Clipboard into a vector. You can join molecules together by dragging the end of one fragment to the end of another. The tool also lets you easily accomplish cloning constructs that were difficult with earlier versions of MacVector. You can easily design and document all subcloning operations from simple digests to complex multi fragment procedures such as Multisite Gateway.

Fig9 pDEST R3R4

Another user request has been for help in documenting the history of a construct. So now all ligation events are documented and saved to the sequence. The Frag feature (in Genbank format) is annotated to the sequence showing the enzymes used, the date and any end modifications.
ClickCloningHistory

There’s also been some significant performance enhancements to the Dot Plot (DNA Matrix) analyses and to the Align To Reference analyses, allowing you to now run pairwise alignments of whole genomes in just a few minutes or to align hundreds of thousands of NGS Reads against a reference genome in an hour or so.

MacVector 12.7 also sees the introduction of a new free basic edition, Macvector Free. You can use MacVector Free to open or download sequences in any supported format, edit them, print, copy sequences, text and graphics, and save in any supported format. This is great for sharing sequences with your non-MacVector using colleagues without having to convert sequences into a common format, often losing information (such as graphical appearance and layout) in the process. Although do remember that MacVector will always export to a full Genbank format sequence. You’ll never be locked out of your data!

CloningClipboard

Due to the requirement for signed applications on Lion and Mountain Lion since Apple introduced Gatekeeper there are two installers.

Download MacVector 12.7 Installer for Leopard (10.5) and Snow Leopard (10.6)

Download MacVector 12.7 Installer for Lion (10.7) and Mountain Lion (10.8)

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