Sequence Analysis Tools for Molecular Biologists
MacVector, Inc. develops powerful but easy to use Macintosh applications for Molecular Biologists to simplify and speed up the analysis, manipulation, assembly and documentation of DNA and protein sequences.
MacVector is a comprehensive Macintosh sequence analysis application that provides sequence editing, primer design, internet database searching, protein analysis, sequence confirmation, multiple sequence alignment, phylogenetic reconstruction, coding region analysis, agarose gel simulation and a variety of other functions. MacVector is widely regarded as the most intuitive, easy to use program available for sequence analysis. More information on MacVector.
Assembler is an add-on DNA sequence assembly module for MacVector that provides a simple graphical interface to the phred, phrap and cross_match contig assembly algorithms from the University of Washington, the popular Bowtie fast reference alignment program for Next Generation Sequencing projects and the Velvet, SPAdes and Flye de novo assemblers for NGS data. Assembler must be purchased separately from MacVector. More details.
If you have relatively minimal sequence editing and analysis needs, or you just want to view, print and/or convert sequence files sent to you by a colleague, do check out our new MacVector Free product. It doesn't have all the advanced bells and whistles of the full release, but it might be just what you are looking for. Note that MacVector Free does require a Macintosh computer running OS X 10.9 or later.
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MacVector 18.1 Released!
MacVector 18.1 is a Universal Binary, capable of running natively on both Intel and Apple Silicon Macintosh computers. Otherwise, it is essentially identical to MacVector 18.0. You can read about the new functionality and check your eligibility. The full installer can be found on this page.
MacVector 18.0 Released!
There is a new CRISPR PAM site searching function, support for new file formats (SnapGene and Sequencher) trim-by-quality for Sanger reads and more enhancements to the MSA domain outlining functionality added in MacVector 17.5. You can read about the new functionality and check your eligibility. The full installer can be found on this page.
macOS 10.16 Big Sur
MacVector 17 and later are not only fully supported and compatible with Apple's latest OS release, macOS Big Sur, but also support Dark Mode and use the latest Apple signing and notarization procedures so you can be sure you are using an authentic copy. Earlier versions of MacVector can't do this. So why not upgrade?
MacVector 17.5 Released!
This release has new functionality for outlining domains in protein multiple sequence alignments, support for quality values in the Align to Reference interface, a new de novo assembly algorithm (Flye) for long read NGS data along with the usual tweaks, bug fixes and support for changes to the macOS. Read about the new functionality here and determine your eligibility for a free update here. The full installer is available to download on this page.
What Has Changed Since My Version?
Check out this link for a list of the new features introduced in each version going all of the way back to MacVector 10.0.
MacVector Cloning Edition
There is a cost-effective version of MacVector available, targeted at users who want the power of MacVector's graphical annotation, clone construction and primer design tools, but without all of the bells and whistles of the full version. Click here for details of the Cloning Edition. Which edition is right for you? Here's a handy functional comparison chart.
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Check out our Getting Started Guide
There's a useful Getting Started Guide to help new users get going with MacVector.
We have a blog with contributions from a selection of MacVector, Inc staff discussing a variety of subjects from OS X through bioinformatics, to the challenges of running a small multi-national company.