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  • macOS Tahoe and MacVector 18.8

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    Apple released macOS Tahoe on Monday (15th Sept 2025). As usual in the run up to a new macOS release, we have been testing MacVector 18.8 on development and public betas of macOS Tahoe. With macOS Tahoe’s Liquid Glass appearance we have come across a very minor display glitch. But otherwise we are happy to…

  • Handling Gaps in Multiple Sequence Alignment Consensus Calculations

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    By default, MacVector ignores gaps when calculating the consensus of a multiple sequence alignment. However, this can lead to some unexpected results. For example, consider this three sequence alignment where one sequence has a long insertion compared to the other two. In this case it does not seem reasonable to believe that the “consensus” should…

  • Automating annotation of sequences via BLAST

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    MacVector 18.8 is out and it’s packed with new tools! MacVector 18.8 has tools to help you identify and annotate unknown, unannotated or partially annotated sequences. Ideal for identifying contigs from a de novo assembly. One of these new tools is AutoAnnotate (via BLAST) Auto-Annotate (via BLAST) is similar to Auto-Annotate (local), except instead of using curated sequences on your own…

  • Optimizing analysis parameters from the results window

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    The majority of MacVector’s analysis tools use a standard workflow: Optimizing results Once you have run the initial analysis then for subsequent analysis you can just repeat the analysis you have just done and further filter it. To do so you need to rerun the analysis tool except now select the Results window (at the…