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  • MacVector video tutorials on You Tube

    There are short video tips on using MacVector on our blog and our YouTube channel. Each one is less than 2 minutes and generally shorter than that! There will be a new screencast every few weeks, so please subscribe to our YouTube channel so you don’t miss any! The latest screencasts include quickly annotating a…

    Read more: MacVector video tutorials on You Tube
    Apr 19, 2018

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    by

    Chris
    in Tips

  • Viewing external database entries for features in a sequence.

    Sequences, or regions of sequences, can be linked to external databases. For example an entire sequence entry or for when annotation tools are used to annotate proteins with domain or motif information (for example InterProScan). Very useful for when you want to view more detailed or updated information. Within the Genbank specification, which MacVector extensively uses,…

    Read more: Viewing external database entries for features in a sequence.
    Apr 19, 2018

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    by

    Chris
    in Tips

  • Use the Replica Button For Synchronized Views

    Most primary MacVector windows (Nucleic Acid Sequence, Protein Sequence, Multiple Sequence Alignment, Align To Reference, Contig Assembly etc.) have a Replica toolbar button. If you click that button, a second window will open, potentially set to a different tab. The key to this functionality is that the two windows are linked – any selections you…

    Read more: Use the Replica Button For Synchronized Views
    Apr 19, 2018

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    by

    Chris
    in Tips

  • How to Identify Bacterial Promoters Using MacVector

    MacVector’s Subsequence tool is a very flexible search function that can be used for a variety of tasks. MacVector itself has a built-in variant of the function for maintaining and search primer databases (Analyze | Primer Database Search…). Each entry in the file MacVector uses as a source of subsequence data can have up to…

    Read more: How to Identify Bacterial Promoters Using MacVector
    Apr 19, 2018

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    by

    Chris
    in Tips

  • Import Multi-Sequence Genbank Files into an Assembly Project for easy access to Features

    There are many genomes in the Genbank database that cannot be downloaded as single annotated sequences. These might be large multi-chromosome eukaryotic genomes, but, increasingly, partially sequenced bacterial chromosomes where the major contigs have been annotated using the NCBI annotation pipeline. Typically, when you encounter these, there are options to download annotated versions of these…

    Read more: Import Multi-Sequence Genbank Files into an Assembly Project for easy access to Features
    Apr 19, 2018

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    by

    Chris
    in Tips

  • Opening multiple sequences as alignments or individual sequences

    Many sequence formats contain multiple concatenated sequence entries. For example FASTA and Genbank are two formats capable of storing multiple individual sequences. By default MacVector will treat such sequences as alignments and open them in the Multiple Sequence Alignment editor. Most users who want to open such a file do want to see an alignment.…

    Read more: Opening multiple sequences as alignments or individual sequences
    Apr 10, 2018

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    by

    Chris
    in Tips

  • Restoring file associations when MacVector no longer opens your sequences

    Macs are pretty good at choosing the right application to open a document. For example when you double click on a .nucl document then it will open in MacVector. However, sometimes this file association breaks. Applications should coexist peacefully on a Mac, but sometimes a misbehaving app will corrupt these file associations and you will…

    Read more: Restoring file associations when MacVector no longer opens your sequences
    Apr 5, 2018

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    by

    Chris
    in Tips

  • What can MacVector do for me?

    Here’s what MacVector can do for your lab. Comparing sequences Whatever type of alignment your sequence needs, there’s a tool in MacVector. CRISPR Indel Analysis: Identify insertions and deletions following CRISPR editing of a target. Sequence assembly of NGS data against a reference genome or compare your sequencing against your new construct. Translated Multiple Sequence…

    Read more: What can MacVector do for me?
    Apr 5, 2018

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    by

    Chris
    in General

  • Searching and downloading sequences from Entrez

    MacVector has integrated connectivity to the NCBI BLAST and Entrez databases. You can directly search Entrez for DNA or Protein sequences based on features, authors, keywords etc and directly download them into MacVector, complete with all features and annotations.

    Read more: Searching and downloading sequences from Entrez
    Jan 26, 2018

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    by

    Chris
    in Tips

  • Eastern Great Lakes workshop tour in February

    The MacVector team will be touring the Eastern Great Lakes for a series of workshops in February. We will be running workshops in Rochester NY, Buffalo NY, Ypsilanti MI, Cleveland OH, Wooster OH, Columbus OH and Cincinnati OH. Monday, Feb. 5th 10:00 – 12:00 University of Rochester, Rochester, NY 2:00 – 4:00 University at Buffalo,…

    Read more: Eastern Great Lakes workshop tour in February
    Jan 25, 2018

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    by

    Chris
    in Meetings
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Workflows

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