Tag: proteins

  • MacVectorTip: How to copy a specific short amino acid translation of a sequence

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    by

    Chris
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    There can be times when you are messing around with open reading frames, inserting residues to change frames to try to get the perfect CDS fusion. The MacVector single sequence Editor will show those (click and hold on the “Display” toolbar button) but if you select and copy, only the DNA sequence (with any overlapping…

  • MacVectorTip: visualizing shared domains in a protein alignment

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    Chris
    in

    MacVector has a domain-outlining facility for multiple sequence alignments, letting you easily visualize the relationships between features in aligned protein sequences.MacVector’s new multiple alignment file format retains the features/annotations from the sequences that are used to create the alignment. The colors of features from the individual sequence documents are used to outline the domains in…

  • MacVector Tip: a complex subsequence pattern example.

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    Chris
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    MacVector’s Subsequence tools allows you to search for motifs in both protein and DNA sequences. As well as a library of existing subsequence files, such as promotors and transcription factor binding sites, you can keep a library of your own subsequence matches. Subsequences libraries are multiple patterns kept in a single file. A search will…

  • MacVector 18.1 and the new InterProScan functional domain analysis tool

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    Chris
    in

    MacVector allows you to do functional domain analysis on your protein sequence using the InterProScan service. InterPro contains multiple databases of protein families, domains and motifs and InterProScan will submit a protein sequence to a search of these databases. It will also do extra analysis such as transmembrane region analysis using TMHMM and other tools.MacVector…

  • Make more of your alignments with MacVector 17.5

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    by

    Chris
    in

    Our latest release MacVector 17.5 gives you new tools to make the most of your alignments. It displays shared domains in protein alignments to visualize the relationships between aligned proteins. It introduces Flye for de novo assembly of PacBio and Oxford Nanopore long reads and a slew of enhancements to the Contig and Align to…