Author: Chris
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MacVector 18.1 and the new InterProScan functional domain analysis tool
MacVector allows you to do functional domain analysis on your protein sequence using the InterProScan service. InterPro contains multiple databases of protein families, domains and motifs and InterProScan will submit a protein sequence to a search of these databases. It will also do extra analysis such as transmembrane region analysis using TMHMM and other tools.MacVector…
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MacVectorTip: Context-sensitive Menus in MacVector
Although Apple are well known (notorious?) for always providing mice with only a single obvious button, in reality the Mac interface from early versions of MacOS all the way to macOS Big Sur, plus many Mac apps, have always used right click menus (or more accurately “context sensitive menus”) to provide extra functionality. MacVector is…
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Make the most of your Apple Silicon Mac with MacVector 18.1
We are very pleased to announce that MacVector 18.1 is now available to download. MacVector 18.1 is a Universal Binary application, which means it runs natively on both Apple Silicon M1 Macs and Intel Macs. MacVector 18.1 matches the “Big Sur” look and feel. …and for the first time in many, many years the MacVector…
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MacVectorTip: Viewing genotype changes in Align to Reference assemblies
The latest releases of MacVector, MacVector 18.0.1 (Intel) and MacVector 18.1.1 (Intel and Apple Silicon) have some tweaks to the output of the SNPs tab in the Align to Reference assembly window. The genotypes of any SNP changes now follow a consistent standard, and short deletions are also reported. If the region containing the nucleotide…
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MacVector on Apple Silicon: benchmarks
MacVector 18.1 has just been released. MacVector 18.1 is a Universal Binary application, which means it runs natively on both Apple Silicon M1 Macs and Intel Macs. MacVector 18.1 also has graphical changes for a more authentic Big Sur look and feel. …and for the first time in many, many years the MacVector icon has…
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CRISPR tools in MacVector
If you are using CRISPR editing techniques then there are two useful functions in MacVector for you: Finding CRISPR Cas9 PAM sites. You can also use Scan DNA FOR.. tool to automatically show sites on all sequences. Screening sequences for CRISPR introduced INDELS
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Using the RE Picker to display restriction enzyme sites in your insert that do not cut your vector.
It’s generally useful with restriction enzyme based cloning to know what restriction enzymes will cut your vector and not cut your insert, or vice versa. There are a few ways to accomplish this with MacVector, but a useful way is to prepare a file of enzymes that do not cut your vector. This is especially…
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MacVector, Apple Silicon and macOS Big Sur compatibility
UPDATE – March 8, 2021 – MacVector 18.1 is now released and can be downloaded. Over twenty years ago Apple called an end to the Classic Mac with the release of OS X, followed five years later by the transition from PowerPC to Intel. A major step forward in the Macintosh world. Earlier this year…
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Virtual Gene Cloning from NGS RNA-Seq Data
The NCBI Sequence Read Archive (SRA) database is a huge resource of Next Generation Sequencing experimental data. Many groups and laboratories deposit data here that they have generated for their own specific projects that can be datamined for other unrelated projects with a minimum of effort. MacVector contains a number of powerful tools that can…
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Working From Home: An overview of primer design workflows in MacVector.
Working from home?. We want to help familiarize you with the wide range of functionality in MacVector that you may never have used before. Here’s an overview of workflows for designing, testing, documenting and storing primers. You may not have a PCR machine on the kitchen table, but why not take the time to store…