Month: May 2026
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MacVectorTip: How to prepare annotated eukaryotic genome assemblies for import into MacVector
One of the more challenging aspects of dealing with large eukaryotic genomes is that most are incomplete and have many gaps. Often the genomes are available as a collection of hundreds or thousands of separate contigs, with associated annotations. This makes working with them awkward. However, increasingly, entire annotated chromosomes can be downloaded with the…
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MacVectorTip: How to view the edit history of your sequence
MacVector’s History tab shows the edit history of your DNA sequences. Some of MacVector’s editing tools will annotate every modification to your sequence. For example with the Cloning Clipboard, all cloning actions (such as ligating a digested fragment into a vector) create a /FRAG feature that records the source of the ligated fragment, the restriction enzymes used to digest it (and…