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Category: Releases

  • de novo assembly with Velvet

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    Chris
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    Velvet is a short read aligner that works very well on a wide variety of reads. Velvet excels at de novo assembly of sequencing reads from second and newer generation sequencers. In our latest release, MacVector 13, we’ve added Velvet to Assembler. This joins the existing tools, Phrap for Sanger sequencing reads and Bowtie for…

  • Calculating the melting temperature of PCR primers

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    Chris
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    Calculating an accurate melting temperature of your oligos, your template and of the predicted product is important to set the cycling parameters of your PCR machine. The Tm calculations in MacVector were updated in MacVector 12.6 to use a more modern algorithm. MacVector has always used thermodynamic “nearest neighbor” calculations, but there were two changes…

  • Testing primers with MacVector 13

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    Chris
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    New to MacVector 13 is the ability to quickly test a pair of primers. Previously to test a pair of primers with the Primer3 tool you needed to modify the expected product and reduce the stringency of all parameters so that your primers would be accepted. Now when you enter a pair of primers into…

  • MacVector 13’s redesigned results windows

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    Chris
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    Before MacVector 13 all the results windows could sometimes get in the way. Some tools, such as the restriction enzyme tool, can generate up to six different results windows. Such as a list of all enzymes that cut a sequence, a list of all non-cutters, a restriction map, etc.. This is all useful information and…

  • Public beta of MacVector 13

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    Chris
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    There’s a public beta of our imminent release MacVector 13 ready for downloading and testing on our website. You just need an active license for MacVector 12.7 to run this. Watch out for the new easier way of installation (no installer, just drag to your Applications folder!). As well as a redesign of the interface…

  • MacVector and Applescript

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    Chris
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    Up to MacVector 13 MacVector has had limited Applescript support. The current release (12.7.5) is able to open sequences, print them and that’s about it! We’ve had frequent requests for MacVector to batch process files. So with the new release (coming very soon) you can batch process files. No analysis can be undertaken just yet…

  • Quicktest Primer and restriction sites

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    Chris
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    With the introduction of the Quicktest Primer tool in MacVector 12.6 primer design became even easier. Being able to slide your primer along a template sequence to see undesirable secondary structure and other attributes in realtime really does make it quicker and straightforward to design good primers. All user feedback we have had say it…

  • MacVector and Mavericks

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    Chris
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    OS X Mavericks was released last week. As usual we’d been testing MacVector on the prerelease developer previews. We did come across a few issues, however, these all seem to be working fine now it’s officially released. So far we’ve done plenty of informal testing with MacVector 12.7.5 and we’ve not come across any major…

  • Season’s greetings from the MacVector team

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    Chris
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    There is no time more fitting to say “Thank You” and to wish you a Happy Holiday Season and a New Year full of health, happiness, and great results from your research. Make sure you put down that pipette and relax , and if you’ve not updated to MacVector 12.7, make sure you take time…

  • MacVector 12.7 is now out.

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    Chris
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    We’re pleased to announce that MacVector 12.7 has just been released. The most exciting new feature is the Cloning Clipboard. We’ve had a lot of user requests over the past few years for help with designing cloning operations and the user feedback we had during the beta testing of MacVector 12.7 makes us think we’ve…