Weekly Tip: Use Hash Value = 12 for speedy genome comparisons with Create Dot Plot

MacVector’s Analyze | Create Dot Plot function can be used to compare entire genomes very quickly to get both an overall view of similarity (large inversions and duplications) while providing the ability to “drill down” to the residue level to see individual SNPs. One of the keys to ensuring the calculations complete in a reasonable […]

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Use dot plots to quickly confirm similarity between two sequences

We occasionally get e-mails from users who think that two sequences should align using ClustalW or the Align To Reference function, but the algorithms cannot find any meaningful matches. In these cases, the first thing I do is open both sequences and then create a dot-plot between them using the Analyze | Create Dotplot | […]

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Alignments in MacVector

Update 19 August 2013: We’ve added support for Muscle and T-Coffee to the MSA editor We get a lot of comments and questions from users on the various alignment functions in MacVector. They say there’s more than one way to skin a cat (not that I’ve done that – I have skinned a catfish, but […]

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