For those of you who like to type in DNA sequences, or do manual editing to the sequences, it’s really useful to be able to see the translations above or below the sequence residues in the Editor tab of the single sequence window. If you are a long term user, you’ll be familiar with the […]
By default, MacVector uses upper case letters for sequence residues. However, you can also use lower case characters if you wish. Changing the case of residues does not affect the MacVector analysis algorithms – GAATTC, gaattc and gAAttC are all considered valid EcoRI sites for example. If you want to set a short region of […]
Following on from my last post about turning on translations in the sequence Editor, I thought I should point out how to display amino acid translations using the 3-letter code rather than the default single-letter code. I don’t know about you, but I have a hard time remembering that “W” is the single-letter IUPAC code […]
MacVector understands the difference between circular DNA molecules and linear DNA molecules. Not just from the standpoint of how the molecule is displayed on the screen, but also in regard to how the analysis algorithms handle the junction at the ends of the circle. The Topology button controls the underlying linear versus circular state of […]
If you download sequences from BLAST or Entrez, or import GenBank or EMBL files with lots of features, you may wish that the features (genes, CDS, promoters etc) showed up differently in the Map tab, or maybe your favorite features don’t show up at all unless you turn them on using the Graphics Palette. Its […]
A feature new to MacVector 12 is the ability to both annotate and display features directly in the Editor, without having to open a separate Map view window. There are also tooltips that show the feature on the sequence directly under the mouse cursor. For example in the following screenshot you see the ID of […]
Sometimes when working on a small subsequence of a much larger sequence it is easier to take that section and make a new file. It is also generally useful in such circumstances to preserve the original numbering. For example if you want to analyse a single gene, but still keep the numbering in the context […]