General musings from the MacVector team about sequence analysis, molecular biology, the Mac in general and of course your favorite sequence analysis app for the Mac!

Category Archives: Uncategorized

Annotating primers to your sequence with MacVector

Designing a pair of primers to amplify a single feature is pretty quick with MacVector. Once you have designed a pair of primers with MacVector, you can quickly annotate both the primers and product to your sequence template. The annotation contains a timestamp and the primer’s characteristics. It also contains the full sequence of the primer, […]

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MacVector are at the ASCB – EMBO 2017 meeting in Philadelphia

The MacVector team will be at the ASCB/EMBO 2017 meeting this coming Sunday. The conference starts on Sunday the 3rd of December and runs until Tuesday the 5th. It’s being held at the Pennsylvania Convention Center. Our booth is 1002. If you are in Philadelphia for the conference please pop along and say “hi!”. We […]

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Turning on/off the SCAN FOR missing Features and ORFs

If you’re running MacVector 15.5 or later then you will have noticed extra features annotated to your sequences. These are from the Scan for ORFs tool (added in MacVector 15.5) and the Scan For Missing Features (added in MacVector 16) tools that automatically scan every DNA sequence window for open reading frames, missing annotations and […]

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Get ready for the release of macOS High Sierra with a 30% discount on all MacVector upgrades

macOS® High Sierra will be released Monday 25th of September. Whether you intend to upgrade early, or months later, you’ll be pleased to know that MacVector 15.5 (the current version) and MacVector 16 (our upcoming release) are both fully supported and compatible with macOS High Sierra. If you are running MacVector 15.5. MacVector 15.5 is […]

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Annotating a gene in MacVector

Creating biologically accurate AND beautiful maps of your plasmids is easy in MacVector. All you need to do is select some sequence, then open the FEATURES EDITOR. Every annotation is fully compatible with the Genbank specification and Feature Table. Tweet

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MacVector 15.5 is out: Graphical BLAST and automatic ORF display.

Our latest release, MacVector 15.5, introduces an entirely new way to view the results of BLAST searches, with an interactive graphical interface that let’s you easily visualize where your query maps to a hit. Unannotated Open Reading Frames are now automatically displayed whenever you open a DNA sequence. A number of changes to the Align […]

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Simple but accurate restriction enzyme based clone construction using Copy and Paste

The quickest and simplest way to create restriction enzyme generated constructs in MacVector is to use Edit | Copy and Edit | Paste. The strategy to use is identical to copying a paragraph from one Microsoft Word document to insert into a second document. i.e. Select the restriction enzymes flanking the source fragment in either […]

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How to change the default appearance of features

If you download a sequence from Entrez, or open a sequence that is not in MacVector format, MacVector assigns a default appearance to any features on the sequence. For example, CDS features are shown as a blue arrow with a Helvetica 9 point font label. With the advent of ultra high resolution displays, you may […]

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Batch auto annotation of blank sequences with MacVector and AppleScript

Over the past few releases we’ve been making more MacVector tools to be scriptable with AppleScript. The latest is Auto Annotation. Auto Annotation is a great tool for curating your sequences. For example if you receive a unannotated sequence then you can scan it against other sequences to find. Blasting an unknown sequence, fetching the […]

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Using the Primer Database to store your lab’s collection of primers

MacVector’s Primer Database allows you to save and retrieve primers from a Primer Database with the Primer3 and Quicktest Primer tools. You can also scan sequences for potential primer binding sites using Primer Database Search. The tool comes with a starter database of primers, but you can use existing subsequence files or import primers from […]

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